| ABUS |    | Arbutus Biopharma Corporation - Common Stock | | | 1.49% up 0.00% 1.49 | | + Biopharma, Medicine, Hepatitis
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| ACER | | Acer Therapeutics Inc. - Common Stock | | | -3.70% down 1.39% -5.09 | | + Medicine, Biopharma
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| ACIU | | AC Immune SA - Common Stock | | | 6.93% 6.93% 0 | | + Disease: Neurology/Alzheimer/Parkinson's, Biopharma, Country: Switzerland
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| ACRS | | Aclaris Therapeutics, Inc. - Common Stock | | | -2.73% up -7.69% 4.96 | | + Immunology, Biopharma, Medicine
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| ADIL | | Adial Pharmaceuticals, Inc - Common Stock | | | 0 | | + Biopharma, Disease: Addictions
- Alcohol
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| ADMP | | Adamis Pharmaceuticals Corporation - Common Stock | | | 0 | | + Respiratory therapies / Pulmanory, Medicine, Biopharma
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| AEZS | | Aeterna Zentaris Inc. - Common Stock | | | -5.45% down 1.36% -6.81 | | + Medicine, Disease: Endocrine disease, Biopharma
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| ALIM | | Alimera Sciences, Inc. - Common Stock | | | 3.69% up -0.82% 4.51 | | + Disease: Eye , Biopharma, Medicine
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| ALRN | | Aileron Therapeutics, Inc. - Common Stock | | | 12.13% down 14.23% -2.1 | | + Cancer fight, Medicine, Biopharma
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| ALT | | Altimmune, Inc. - Common Stock | | | -9.24% down -2.95% -6.29 | | + Immunology, Biopharma, Medicine
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| ARTL | | Artelo Biosciences, Inc. - Common Stock | | | -2.70% down 1.69% -4.39 | | + Biopharma, Medicine
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| ARWR | | Arrowhead Pharmaceuticals, Inc. - Common Stock | | | -1.59% down 0.32% -1.91 | | + Biopharma, RNA, Medicine
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| ASLN | | ASLAN Pharmaceuticals Limited - American Depositary Shares | | | 0 | | + Country: Singapore, Pharmaceutical , Biopharma, Immunology, Medicine
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| ASMB | | Assembly Biosciences, Inc. - Common Stock | | | -1.92% down 1.28% -3.2 | | + Disease: Infectious, Medicine, Biopharma
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| ATNX | | Athenex, Inc. - Common Stock | | | 0 | | + Cancer fight, Biopharma, Covid (fighting)
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| AVIR | | Atea Pharmaceuticals, Inc. - common stock | | | -2.85% down -0.48% -2.37 | | + Biopharma
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| BDSX | | Biodesix, Inc. - Common Stock | | | 8.65% up 3.78% 4.87 | | + Biopharma, Medicine, Diagnosing, Disease: Lung
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| BLCM | | Bellicum Pharmaceuticals, Inc. - Common Stock | | | 4.92% down 7.38% -2.46 | | + Biopharma, Medicine, Immunology
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| BNTC | | Benitec Biopharma Inc. - Common Stock | | | 0 | | + Biopharma, Biotechnology, RNA, Medicine, Gene and cell
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| BTAI | | BioXcel Therapeutics, Inc. - Common Stock | | | 0.12% down 1.56% -1.44 | | + Medicine, Immunology, Artificial Intelligence, Biopharma
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| BVXV | | BiondVax Pharmaceuticals Ltd. - American Depositary Shares | | | -1.21% down 1.61% -2.82 | | + Biopharma, Medicine, Disease: Infectious
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| BXRX | | Baudax Bio, Inc. - Common stock | | | 22.71% up 10.76% 11.95 | | + Surgery, Medicine, Biopharma
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| BYSI | | BeyondSpring, Inc. - Ordinary Shares | | | 6.1% down 7.51% -1.41 | | + Cancer fight, Biopharma, Medicine, Immunology
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| CBIO | | Catalyst Biosciences, Inc. - Common Stock | | | 0 | | + Biopharma, Medicine
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| CDAK | | Codiak BioSciences, Inc. - Common Stock | | | 84.43% 84.43% 0 | | + Medicine, Biopharma
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| CDNA | | CareDx, Inc. - Common Stock | | | 4.18% up 2.92% 1.26 | | + Medicine, Biopharma, Transplant
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| CLLS | | Cellectis S.A. - American Depositary Shares | | | 104.11% 104.11% 0 | | + Biopharma, Medicine, Cancer fight
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| CLRB | | Cellectar Biosciences, Inc. - Common Stock | | | -2.92% down -1.75% -1.17 | | + Medicine, Biopharma, Cancer fight
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| CLSD | | Clearside Biomedical, Inc. - Common Stock | | | 96.32% 96.32% 0 | | + Disease: Eye , Medicine, Biopharma
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| CNCE | | Concert Pharmaceuticals, Inc. - Common Stock | | | 0.36% up 0.00% 0.36 | | + Biopharma, Medicine
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| CNTB | | Connect Biopharma Holdings Limited - American Depositary Shares | | | -7.27% -7.27% 0 | | + Biopharma, Country: China, T cell-based
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| CTMX | | CytomX Therapeutics, Inc. - Common Stock | | | -6.07% down -4.45% -1.62 | | + Biopharma, Cancer fight, Disease: Oncology
- Bad infrastructure
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| CUE | | Cue Biopharma, Inc. - Common Stock | | | 100% 100% 0 | | + Biopharma, Immunology, Cancer fight
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| CVAC | | CureVac N.V. - Ordinary Shares | | | 101.09% 101.09% 0 | | + Country: Germany, RNA, Medicine, Biopharma
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| CYCC | | Cyclacel Pharmaceuticals, Inc. - Common Stock | | | -0.95% up -1.90% 0.95 | | + Biotechnology, Biopharma, Pharmaceutical , Medicine, Gene and cell
- Bad infrastructure
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| CYCCP | | Cyclacel Pharmaceuticals, Inc. - 6% Convertible Preferred Stock | | | -7.92% -7.92% 0 | | + Cancer fight, Medicine, Biopharma
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| DBVT | | DBV Technologies S.A. - American Depositary Shares | | | 95.47% 95.47% 0 | | + Immunology, Biopharma, Medicine
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| DMAC | | DiaMedica Therapeutics Inc. - Common Stock | | | -1.97% down 7.24% -9.21 | | + Biopharma, Disease: Kidney, Medicine, Disease: Acute ischemic stroke (AIS)
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| DRRX | | DURECT Corporation - Common Stock | | | -1.7% up -7.95% 6.25 | | + Biopharma, Disease: Liver, Medicine
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| DVAX | | Dynavax Technologies Corporation - Common Stock | | | 1.77% up 0.00% 1.77 | | + Immunology, Biology, Biopharma, Medicine, Vaccines
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| DYAI | | Dyadic International, Inc. - Common Stock | | | -5.22% -5.22% 0 | | + Medicine, Biopharma, Pharmaceutical
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| EDSA | | Edesa Biotech, Inc. - Common Shares | | | 3.60% down 4.32% -0.72 | | + Medicine, Biopharma, Immunology
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| EIGR | | Eiger BioPharmaceuticals, Inc. - Common Stock | | | -7.02% -7.02% 0 | | + Medicine, Biopharma
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| ELOX | | Eloxx Pharmaceuticals, Inc. - Common Stock | | | -2.26% down 0.25% -2.51 | | + Biopharma, Medicine, RNA
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| ETNB | | 89bio, Inc. - Common Stock | | | 31.8% up 29.4% 2.4 | | + Biopharma, Disease: Liver, Medicine
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| EYEN | | Eyenovia, Inc. - Common Stock | | | 12.45% up 9.43% 3.02 | | + Medicine, Biopharma
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| EYPT | | EyePoint Pharmaceuticals, Inc. - Common Stock | | | -9.31% down -3.19% -6.12 | | + Pharmaceutical , Disease: Eye , Medicine, Biopharma
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| FBIO | | Fortress Biotech, Inc. - Common Stock | | | 0 | | + Pharmaceutical , Biopharma, Biotechnology, Medicine
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| FBIOP | | Fortress Biotech, Inc. - 9.375% Series A Cumulative Redeemable Perpetual Preferred Stock | | | -0.76% down 0.46% -1.22 | | + Medicine, Biotechnology, Biopharma
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| FBRX | | Forte Biosciences, Inc. - Common Stock | | | -0.99% down 0.00% -0.99 | | + Skin, Medicine, Disease: Infectious, Biopharma
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| FOLD | | Amicus Therapeutics, Inc. - Common Stock | | | 99.21% 99.21% 0 | | + Biopharma, Medicine
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| GLMD | | Galmed Pharmaceuticals Ltd. - Ordinary Shares | | | 0 | | + Disease: Liver, Biopharma, Country: Israel, Medicine
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| GLSI | | Greenwich LifeSciences, Inc. - Common stock | | | -0.45% up -7.71% 7.26 | | + Medicine, Biopharma, Cancer fight, Immunology
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| GNFT | | GENFIT S.A. - American Depositary Shares | | | 99.78% 99.78% 0 | | + Biopharma, Disease: Liver, Medicine
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| GTBP | | GT Biopharma, Inc. - Common Stock | | | 0 | | + Biopharma, Medicine, Disease: Oncology, Immunology, Cancer fight
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| HGEN | | Humanigen, Inc. - Common Stock | | | 0 | | + Biopharma, Immunology, Cancer fight, Medicine
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| HOTH | | Hoth Therapeutics, Inc. - Common Stock | | | 3.76% down 9.02% -5.26 | | + Medicine, Biopharma, Skin
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| ICPT | | Intercept Pharmaceuticals, Inc. - Common Stock | | | 3.69% 3.69% 0 | | + Pharmaceutical , Medicine, Biopharma, Disease: Liver
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| IMAB | | I-MAB - American Depositary Shares | | | -10.94% down -5.08% -5.86 | | + Country: China, Biopharma, Medicine
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| IMRN | | Immuron Limited - American Depositary Shares | | | 10% 10% 0 | | + Biotechnology, Country: Australia, Biopharma, Medicine
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| IMV | | IMV Inc. - Common Shares | | | -33.08% down -5.26% -27.82 | | + Immunology, Medicine, Country: Canada, Covid (fighting), Biopharma
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| INSM | | Insmed, Inc. - Common Stock | | | 2.92% up 0.81% 2.11 | | + Biopharma, Medicine
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| ISEE | | IVERIC bio, Inc. - Common Stock | | | 100.27% 100.27% 0 | | + Medicine, Biopharma
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| ITOS | | iTeos Therapeutics, Inc. - Common Stock | | | -7.47% -7.47% 0 | | + Cancer fight, Biopharma, Disease: Oncology, Immunology, Medicine
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| JAGX | | Jaguar Health, Inc. - Common Stock | | | -22.61% down -19.85% -2.76 | | + Medicine, Biopharma, Agritech
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| KALA | | Kala Pharmaceuticals, Inc. - Common Stock | | | -13.62% -13.62% 0 | | + Disease: Eye , Disease: Gastrointestinal, Medicine, Biopharma
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| KMDA | | Kamada Ltd. - Ordinary Shares | | | 2.86% up 0.71% 2.15 | | + Biopharma, Pharmaceutical , Medicine
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| KNSA | | Kiniksa Pharmaceuticals, Ltd. - Class A Common Stock | | | -2.03% down -0.73% -1.3 | | + Pharmaceutical , Biopharma, Medicine
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| KOD | | Kodiak Sciences Inc - Common Stock | | | 103.26% 103.26% 0 | | + Biopharma, Disease: Eye , Medicine
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| KRBP | | Kiromic BioPharma, Inc. - Common Stock | | | 0 | | + Biopharma, Cancer fight, Immunology, Medicine
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| KROS | | Keros Therapeutics, Inc. - common stock | | | 7.02% up -1.94% 8.96 | | + Biopharma, Medicine, Hematologic and musculoskeletal disorders
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| KYMR | | Kymera Therapeutics, Inc. - Common Stock | | | 0.09% up -0.91% 1 | | + Biopharma, Medicine
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| LABP | | Landos Biopharma, Inc. - Common Stock | | | 0 | | + Biopharma, Medicine
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| LEXX | | Lexaria Bioscience Corp. - Common Stock | | | 8.89% up 0.37% 8.52 | | + Biopharma, Medicine, Cannabinoid-based
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| LQDA | | Liquidia Technologies, Inc. - Common Stock | | | -4.3% -4.3% 0 | | + Medicine, Biopharma, Respiratory therapies / Pulmanory
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| MASS | | 908 Devices Inc. - Common Stock | | | -0.68% up -0.77% 0.09 | | + Devices, Biopharma, Life Sciences
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| MDWD | | MediWound Ltd. - Ordinary Shares | | | 4.79% up 3.09% 1.7 | | + Biopharma
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| MNPR | | Monopar Therapeutics Inc. - Common Stock | | | -8.13% up -9.49% 1.36 | | + Cancer fight, Medicine, Biopharma
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| MOR | | MorphoSys AG - American Depositary Shares | | | 0.80% down 1.00% -0.2 | | + Biopharma, Medicine, Disease: Oncology, Immunology, Cancer fight
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| MREO | | Mereo BioPharma Group plc - American Depositary Shares | | | -8.65% down -6.73% -1.92 | | + Biopharma, Cancer fight, Country: Greate Britain
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| NGM | | NGM Biopharmaceuticals, Inc. - Common Stock | | | -8.02% down -4.5% -3.52 | | + Biopharma, Medicine
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| NMTR | | 9 Meters Biopharma, Inc. - Common Stock | | | -9.26% -9.26% 0 | | + Biopharma, Medicine, Disease: Bowel syndrome, Disease: Celiac
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| NTLA | | Intellia Therapeutics, Inc. - Common Stock | | | 1.11% down 1.84% -0.73 | | + Medicine, Gene and cell, Biotechnology, Biopharma
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| OCUP | | Ocuphire Pharma, Inc. - Common Stock | | | 12.73% 12.73% 0 | | + Disease: Eye , Biopharma, Medicine, Pharmaceutical
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| OLK | | Olink Holding AB (publ) - American Depositary Shares | | | 5.96% up 1.70% 4.26 | | + Biology, Biopharma, Medicine, Country: Sweden
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| OMER | | Omeros Corporation - Common Stock | | | up -11.49% 11.49 | | + Biopharma, Biotechnology, Medicine
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| OTLK | | Outlook Therapeutics, Inc. - Common Stock | | | 108.93% 108.93% 0 | | + Disease: Eye , Biopharma, Medicine
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| PGEN | | Precigen, Inc. - Common Stock | | | -8.62% down -4.6% -4.02 | | + Biopharma, Gene and cell, Medicine
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| PIRS | | Pieris Pharmaceuticals, Inc. - Common Stock | | | -7.06% down -5.29% -1.77 | | + Biopharma, Respiratory therapies / Pulmanory, Medicine, Immunology, Cancer fight
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| PLRX | | Pliant Therapeutics, Inc. - Common Stock | | | 0.55% up 0.35% 0.2 | | + Biopharma, Medicine
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| PRAX | | Praxis Precision Medicines, Inc. - Common Stock | | | -7.05% -7.05% 0 | | + Biopharma, Gene and cell, Disease: Central nervous system (CNS), Medicine
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| PRTK | | Paratek Pharmaceuticals, Inc. - Common Stock | | | 1.01% up 0.00% 1.01 | | + Pharmaceutical , Biopharma, Medicine, Life Sciences
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| RGLS | | Regulus Therapeutics Inc. - Common Stock | | | -10.27% -10.27% 0 | | + RNA, Biopharma, Medicine
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| RVPH | | Reviva Pharmaceuticals Holdings, Inc. - Common Stock | | | -8.15% -8.15% 0 | | + Medicine, Biopharma, Pharmaceutical , Disease: Metabolic disorders, Disease: Central nervous system (CNS), Respiratory therapies / Pulmanory
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| RZLT | | Rezolute, Inc. - Common Stock | | | -7.43% down -3.72% -3.71 | | + Biopharma, Medicine, Disease: Hypoglycemia
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| SAVA | | Cassava Sciences, Inc. - Common Stock | | | -7.44% down -2.85% -4.59 | | + Disease: Neurology/Alzheimer/Parkinson's, Medicine, Biopharma
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| SPRO | | Spero Therapeutics, Inc. - Common Stock | | | 100% 100% 0 | | + Disease: Infectious, Biopharma, Medicine
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| TCON | | TRACON Pharmaceuticals, Inc. - Common Stock | | | down 0.60% -0.6 | | + Pharmaceutical , Cancer fight, Medicine, Biopharma, Disease: Oncology
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| TERN | | Terns Pharmaceuticals, Inc. - Common Stock | | | 9.57% down 10% -0.43 | | + Biopharma, Pharmaceutical , Disease: Liver
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| THTX | | Theratechnologies Inc. - Common Shares | | | 0 | | + Cancer fight, Biopharma, Medicine
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| TLRY | | Tilray, Inc. - Class 2 Common Stock | | | 7.67% up 3.14% 4.53 | | + Biopharma, Cannabis, Medicine, Country: Canada, Reddit's Wave
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| TNXP | | Tonix Pharmaceuticals Holding Corp. - Common Stock | | | 1.90% 1.90% 0 | | + Medicine, Biopharma, Immunology, Disease: Addictions, Disease: Neurology/Alzheimer/Parkinson's, Disease: Central nervous system (CNS)
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| TRVN | | Trevena, Inc. - Common Stock | | | -10.66% -10.66% 0 | | + Biopharma, Medicine, Disease: Central nervous system (CNS)
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| TTNP | | Titan Pharmaceuticals, Inc. - Common Stock | | | 0 | | + Biopharma, Disease: Central nervous system (CNS), Medicine
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| TVTX | | Travere Therapeutics, Inc. - Common Stock | | | -5.14% down -1.93% -3.21 | | + Biopharma, Medicine
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| VBLT | | Vascular Biogenics Ltd. - Ordinary Shares | | | 0 | | + Country: Israel, Biopharma, Cancer fight, Medicine
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| VCEL | | Vericel Corporation - Common Stock | | | 6.73% 6.73% 0 | | + Biopharma, Medicine, Sport
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| VINC | | Vincerx Pharma, Inc. - Common Stock | | | -7.2% down -5.6% -1.6 | | + Biopharma, Medicine, Life Sciences
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| VOR | | Vor Biopharma Inc. - Common Stock | | | 7.32% up 6.94% 0.38 | | + Biopharma, Medicine, Cancer fight, Disease: Oncology
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| VSTM | | Verastem, Inc. - Common Stock | | | 0 | | + Biopharma, Cancer fight, Medicine
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| WINT | | Windtree Therapeutics, Inc. - Common Stock | | | 0 | | + Biopharma, Respiratory therapies / Pulmanory, Medicine
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| XAIR | | Beyond Air, Inc. - Common Stock | | | -8.04% down -8.04 | | + Respiratory therapies / Pulmanory, Medicine, Biopharma
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| XBIO | | Xenetic Biosciences, Inc. - Common Stock | | | 0 | | + Biopharma, Cancer fight, Disease: Oncology, Medicine
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| YMAB | | Y-mAbs Therapeutics, Inc. - Common Stock | | | up -1.86% 1.86 | | + Biopharma, Cancer fight, Medicine
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